Oxymetazoline
THE VASOCONSTRICTOR
A prescription active that works directly on the blood vessels behind facial redness, visibly reducing flushing within hours of application. The active that works at the blood vessel.Rosacea · Same-Day Redness Control
The Redness Control Formula Rx
Oxymetazoline · Niacinamide
For redness you need handled today, not in a few weeks.
$34.50/month
Starting with a 2-month supply
- Free shipping
- Skip or delay refills
- HSA/FSA eligible
- Ongoing support
Rosacea · Same-Day Redness Control
The Redness Control Formula Rx
Oxymetazoline · Niacinamide
For redness you need handled today, not in a few weeks.
$34.50/month
Starting with a 2-month supply
Oxymetazoline visibly reduces redness and flushing within hours of the first application. Niacinamide strengthens the barrier and reduces the appearance of visible redness with daily use. The formula layers over your ongoing rosacea treatment rather than replacing it.
Reduces the appearance of:
- Free shipping
- Skip or delay refills
- HSA/FSA eligible
- Ongoing support
Formulations
The Redness Control Formulaᴿˣ is a single standard formulation. Oxymetazoline 1% is the prescription active that reduces visible redness, at the same concentration used in the FDA-approved treatment for facial redness in rosacea. Niacinamide 2% supports the skin barrier. Centella asiatica and ceramides are included to keep the formula comfortable for daily use.
Active ingredients:
- Oxymetazoline HCl 1%
- Niacinamide 2%
Supporting ingredients:
- Centella asiatica
- Ceramides
Compounded medications are not FDA-approved.
How & Why It Works
- Oxymetazoline narrows the dilated blood vessels that make your face look red, visibly reducing redness and flushing within hours of application
- Niacinamide strengthens the skin barrier and reduces the appearance of visible redness with daily use
- Centella asiatica helps keep skin comfortable during daily use
- Ceramides support the skin barrier and help it hold moisture
- Oxymetazoline works on how red your skin looks rather than on the inflammation underneath, so the formula layers over your ongoing rosacea treatment rather than replacing it
- Compounded by a licensed pharmacy for each prescription
How to Use
Apply a thin layer to clean, dry skin once daily in the morning. Wait 15 to 20 minutes for it to absorb, then apply your moisturizer, SPF, and makeup as usual.
Use it on the forehead, nose, cheeks, and chin. Avoid the eyes, lips, and any broken or irritated skin.
Oxymetazoline visibly reduces redness within 30 minutes to 3 hours of application, and the effect lasts through most of the day.
Wear a broad-spectrum sunscreen, minimum SPF 30, every morning.
- One bottle is approximately a 2-month supply
Pairs Well With
The Redness & Acne Formula
A prescription formula for rosacea with breakouts and the marks they leave behind. Azelaic acid works on the bumps over weeks while Redness Control handles visible redness the same day.
A prescription formula for rosacea with breakouts and the marks they leave behind.
The Advanced Redness Solution
A three-active prescription formula for the bumps, pustules, and inflammation of persistent rosacea. It works on what is driving the flare while Redness Control reduces how red your skin looks during the day.
A three-active prescription formula for the bumps, pustules, and inflammation of persistent rosacea.
100% Compounded Online PharmacyPrescription-Only TreatmentsNo Long-Term Commitments
What's The Redness Control Formula?
Oxymetazoline visibly reduces redness and flushing within hours of the first application. Niacinamide strengthens the barrier and reduces the appearance of visible redness with daily use. The formula layers over your ongoing rosacea treatment rather than replacing it.
Reduces the appearance of:
- Free shipping
- Skip or delay refills
- HSA/FSA eligible
- Ongoing support
Formulations
The Redness Control Formulaᴿˣ is a single standard formulation. Oxymetazoline 1% is the prescription active that reduces visible redness, at the same concentration used in the FDA-approved treatment for facial redness in rosacea. Niacinamide 2% supports the skin barrier. Centella asiatica and ceramides are included to keep the formula comfortable for daily use.
Active ingredients:
- Oxymetazoline HCl 1%
- Niacinamide 2%
Supporting ingredients:
- Centella asiatica
- Ceramides
Compounded medications are not FDA-approved.
How & Why It Works
- Oxymetazoline narrows the dilated blood vessels that make your face look red, visibly reducing redness and flushing within hours of application
- Niacinamide strengthens the skin barrier and reduces the appearance of visible redness with daily use
- Centella asiatica helps keep skin comfortable during daily use
- Ceramides support the skin barrier and help it hold moisture
- Oxymetazoline works on how red your skin looks rather than on the inflammation underneath, so the formula layers over your ongoing rosacea treatment rather than replacing it
- Compounded by a licensed pharmacy for each prescription
How to Use
Apply a thin layer to clean, dry skin once daily in the morning. Wait 15 to 20 minutes for it to absorb, then apply your moisturizer, SPF, and makeup as usual.
Use it on the forehead, nose, cheeks, and chin. Avoid the eyes, lips, and any broken or irritated skin.
Oxymetazoline visibly reduces redness within 30 minutes to 3 hours of application, and the effect lasts through most of the day.
Wear a broad-spectrum sunscreen, minimum SPF 30, every morning.
- One bottle is approximately a 2-month supply
Pairs Well With
The Redness & Acne Formula
A prescription formula for rosacea with breakouts and the marks they leave behind. Azelaic acid works on the bumps over weeks while Redness Control handles visible redness the same day.
A prescription formula for rosacea with breakouts and the marks they leave behind.
The Advanced Redness Solution
A three-active prescription formula for the bumps, pustules, and inflammation of persistent rosacea. It works on what is driving the flare while Redness Control reduces how red your skin looks during the day.
A three-active prescription formula for the bumps, pustules, and inflammation of persistent rosacea.
The clinical team
The medicine behind your prescription is built by the doctors you already follow.
The Redness Control Formula Rx wasn't formulated by an algorithm or pulled from a generic template. Its protocol was designed by Dr. Lindsey Zubritsky, Dr. Mamina Turegano, and Dr. Jenny Liu, three board-certified dermatologists with decades of combined experience treating real people.
Your prescription is then written by a board-certified dermatologist on our clinical team, working from the protocol they built. Dermatologist-built medicine, delivered to your door.
Dr. Lindsey Zubritsky MDDr. Mamina Turegano, MDDr. Jenny Liu, MD
What's in the bottle
Real actives. Named, not hidden.
The Redness Control Formula Rx pairs two prescription actives with two supporting ingredients, built for visible daytime relief, with the barrier protection that holds it.
Active Ingredients
Niacinamide
THE BARRIER SUPPORT
A form of vitamin B3 that strengthens the skin barrier and reduces the appearance of visible redness, supporting a calmer, more even complexion.Supporting Ingredients
Centella Asiatica
THE CALMER
A clinically studied botanical that helps keep skin comfortable. Used in dermatology for decades, the quiet ingredient that keeps the strong ones comfortable.
Ceramides
THE BARRIER REPAIR
Lipids that reinforce the skin barrier and lock in moisture, helping skin stay comfortable through daily use.
Compounded medications are not FDA-approved.
What to expect
Same-day visible relief, designed to layer with your treatment.
The Redness Control Formula Rx is designed around the visible appearance of redness (the symptom) while your ongoing rosacea formula supports the broader skin pattern.
Oxymetazoline works on the blood vessels in your skin to reduce flushing and visible redness within hours, with the effect lasting through most of the day, and with niacinamide, Centella asiatica, and ceramides supporting the barrier.
- Visibly reduces facial redness within hours of application
- Reduces flushing and visible redness through the day
- Layers with ongoing rosacea treatments without interference
- Supports the skin barrier with daily use
- Focuses on visible redness and flushing, not bumps or pustules
Built for the woman who needs
her face to calm down, today.
Oxymetazoline visibly reduces redness within hours rather than weeks. It acts directly on blood vessels to reduce visible redness and flushing on the days you can't afford to look flared. It's designed to layer on top of your underlying rosacea treatment, not replace it. Think of it as daytime symptom control while your root-cause treatment does its slow work.
Ideal for you if you're
Noticing visible facial redness that shows up in every photo and meeting
Experiencing flushing or facial redness that worsens with heat, sun, or stress
Looking for a daytime formula to layer with an ongoing rosacea treatment
Needing same-day visible relief for events, meetings, or photos
Interested in targeted symptom control, as confirmed during your assessment
Consider a different fit if you're:
Living with a heart, circulation, blood pressure, or eye condition, or taking MAO inhibitors or tricyclic antidepressants. Oxymetazoline narrows blood vessels, so a board-certified dermatologist on our clinical team will review your medical history before prescribing. Read the full safety information →
Pregnant, nursing, or trying to conceive. The Redness & Acne Formulaᴿˣ is built around azelaic acid and may be the better fit
Dealing with bumps or pustules rather than redness. The Advanced Redness Solutionᴿˣ or The Clarifying Rosacea Formulaᴿˣ is built for that
Dealing with discrete marks where individual spots used to be. The Red Mark Solutionᴿˣ is built for post-inflammatory erythema
What our customers are saying.
BeforeAfter
No makeup, no touchups
★★★★★
“I finally have something for the days my face decides to turn bright red.”
“My biggest issue has always been flushing. Heat, stress, walking outside, even a hot shower could leave my cheeks and nose bright red for hours. I started using this in the morning and the difference in how my skin looks during the day has been incredible. I still have sensitive skin, but the redness is so much less noticeable. I finally feel like I have some control over it.”
Celine
BeforeAfter
No makeup, no touchups
★★★★★
“The difference within the same day surprised me.”
“I was used to skincare taking weeks or months before I could tell if it was doing anything, so I wasn't expecting much at first. What surprised me was seeing my facial redness look noticeably calmer after using this. I especially notice it across my nose and cheeks, which are usually the first places to turn red. This has become part of my morning routine.”
Marissa K.
BeforeAfter
No makeup, no touchups
★★★★★
“I don't think about my red face in every meeting anymore.”
“Stress is one of my biggest triggers and I used to get incredibly self-conscious because I could literally feel my face getting hotter and redder during meetings. Since adding this to my routine, the visible redness is much easier to manage. My skin doesn't look perfect and I still flush sometimes, but it's nowhere near as obvious as it used to be. That's exactly what I wanted.”
Tessa R.
BeforeAfter
No makeup, no touchups
★★★★★
“This has made such a difference in how my skin looks during the day.”
“My redness is mostly concentrated around my cheeks and nose and gets much worse when I'm warm. I had tried so many calming skincare products without getting the visible improvement I wanted. With this formula, my complexion looks much more even during the day. I still recognize my skin. It just doesn't look constantly flushed anymore.”
Alana
BeforeAfter
No makeup, no touchups
★★★★★
“My skin can still be sensitive without looking intensely red all day.”
“That was the biggest difference for me. I wasn't expecting my sensitive skin to suddenly disappear, I just wanted to stop looking so flushed all the time. After adding this to my morning routine, my cheeks look noticeably calmer and more even. I especially appreciate it on work days or when I know I'm going to be photographed.”
Jiwoo P.
BeforeAfter
No makeup, no touchups
★★★★★
“I wish I had known there was an option like this years ago.”
“I've dealt with visible redness for years and assumed covering it with makeup was basically my only option. This has completely changed how I manage it. My face looks significantly less red during the day, especially around my cheeks and nose. I don't feel like I need to immediately reach for concealer every morning anymore.”
Nia W.
Realistic timeline
What you may see, fast.
Unlike most rosacea treatments, oxymetazoline works visibly the same day.
Here's what most people experience.
Results vary. Timelines depend on your starting skin, your formula strength, and how consistently you apply your treatment.
Day 1
Initial application
Apply a thin layer in the morning. Visible redness reduction typically begins within 30 minutes to 3 hours and continues through the day. Some people see fuller results across the first few days as they refine their application.Week 1
Refinement
You'll learn how much to apply, when in your morning routine, and how to layer with your other rosacea treatment. A board-certified dermatologist on our clinical team can adjust your protocol based on what you're seeing.Weeks 2–4
Steady control
Daily use produces consistent daytime redness control. The barrier-supporting ingredients (niacinamide, ceramides, Centella asiatica) also strengthen the barrier with continued use.Ongoing
Long-term use
Oxymetazoline is designed for ongoing daily use as long as a board-certified dermatologist on our clinical team confirms it remains appropriate. Pair it with your underlying treatment and SPF, and a board-certified dermatologist on our clinical team checks in to adjust as needed.Results vary. Timelines depend on your starting skin, your formula strength, and how consistently you apply your treatment.
How it works
Three steps. No appointments. Reviewed by a board-certified dermatologist within one business day.
Tell us about your skin.
Take our skin assessment. Share your concerns, your skin's history, what you've tried before, and a few photos. The more we know, the better the formula.
One business day review
Your case is reviewed within one business day, and your prescription is written by a board-certified dermatologist on our clinical team.
Oxymetazoline
NiacinamideYour prescription arrives
Your formula is compounded by a licensed pharmacy and shipped to your door, usually within a week. Your dermatologist stays with you, adjusting your formula as your skin responds.
Frequently Asked Questions
How is this different from the other rosacea formulas?
Oxymetazoline is the only active in the rosacea line that works visibly the same day. The Redness & Acne Formulaᴿˣ, The Advanced Redness Solutionᴿˣ, and The Clarifying Rosacea Formulaᴿˣ are built for ongoing rosacea-prone skin concerns, including papules, pustules, and acne-like breakouts. They work on a timeline of weeks. The Redness Control Formulaᴿˣ uses oxymetazoline to visibly reduce redness through vasoconstriction. It is designed around the appearance of redness, not deeper flare support. Most people use it alongside an ongoing rosacea formula.
Can I use this alone, without another rosacea treatment?
Some people do, particularly if their primary concern is visible flushing and vascular redness without significant papules, pustules, or breakouts. But for most rosacea-prone skin, the best results come from pairing The Redness Control Formulaᴿˣ with an ongoing formula selected for their broader skin pattern. A board-certified dermatologist on our clinical team will assess your case during the assessment and recommend whether to add another formula.
How fast does it actually work?
Most people see visible redness reduction within 30 minutes to 3 hours of application. The peak effect typically lasts through most of the day. Some people see fuller results across the first few days of use as they refine application amount and timing. Individual response varies. A board-certified dermatologist on our clinical team can help you optimize your protocol if results aren't holding.
Are there cardiovascular risks I should know about?
Yes. Oxymetazoline is a vasoconstrictor, and there are important considerations. It's not recommended for people with a history of cardiovascular disease, severe hypertension, Raynaud's syndrome, or for those taking MAO inhibitors. A board-certified dermatologist on our clinical team will review your medical history during your assessment to confirm this is safe for you. Read the full Important Safety Information before starting treatment.
Can I wear makeup over it?
Yes. Apply The Redness Control Formulaᴿˣ to clean, dry skin in the morning, wait 15 to 20 minutes for it to absorb fully, then apply your moisturizer, SPF, and makeup as usual. Many people find the formula creates a smoother base for makeup application because the skin underneath is visibly calmer.
Can I use this if I'm pregnant?
No. Oxymetazoline is not recommended during pregnancy or nursing. If you're pregnant, planning to be, or nursing, The Redness & Acne Formulaᴿˣ (built around azelaic acid) is the pregnancy-safe rosacea option in our lineup. If your pregnancy status changes during treatment, contact your DermClick care team immediately so your prescription can be adjusted.
What happens if I stop using it?
Because oxymetazoline works by narrowing blood vessels rather than treating the rosacea itself, your baseline redness returns when you stop. Some people notice their skin looks redder than usual for a short period after stopping, which is called rebound redness. It's uncommon with oxymetazoline, and it settles on its own. If you want to stop, message your DermClick care team first so a board-certified dermatologist on our clinical team can advise on how to taper off and what to use instead.
The Redness Control Formula Rx is built for visible daytime relief. If you also need support for broader rosacea-prone skin concerns (papules, pustules, reactivity, or acne-like breakouts), these are the formulas that pair most naturally with it.
